In a recent article in the British Journal of Psychiatry (2015, 206: 93-100) Mathew Hoskins et al state that based on a systematic review there are small but significant differences in medication effect. Mainly, Fluoxetine, Paroxetine and Venlafaxine were found to be efficient.

In the February 2014 edition of the British Journal of Psychiatry (BJPsych204, 144-150) Marco Menchetti and colleagues form the university of Bologna found that the percentage of patients achieving remission was higher in the Interpersonal Therapy Group than with medication (SSRIs) alone. Five moderators were found for the psychotherapy subgroup: Depression severity (-), functional impairment (-), anxiety comorbidity (-), previous depressive episodes (-) and smoking (+), the last possibly because smoking interacts with medication in negative way.

In a recent review article in the British Journal of Psychiatry (2013, 203: 327-333) P.A. Garety and D. Freeman argue that the focus of intervention and research in delusional disorders should rather be on the individual experience of psychosis than on diagnostic categories. They also identified mediating or modiying factors for distress of the individual’s delusion, e.g. poor self-esteem, worry, insomnia, feelings of pwerlessness, poor belief-flexibility and jumping to conclusions. In regard to Cognitive Behaviour Therapy (CBT) for psychosis, the existence of a carer was associated with a better outcome.